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The enrolled patients were usually males In the resting state studies, the more relevant abnormalities were localized in the superior temporal gyrus, limbic, medial frontal and parietal regions. When analyzing the task related fmri studies, we found that less than half of the papers reported behavioral differences between patients and normal controls, but all of them found significant differences in cortical and subcortical brain regions involved in cognitive control and reward processing: Orbitofrontal cortex, insula, anterior and posterior cingulate cortex, temporal and parietal regions, brain stem and caudate nucleus.

It needs to be studied more in depth to provide a clear diagnosis and an adequate treatment. Internet addiction, Pathologic internet use, Functional magnetic resonance imaging, Internet gaming disorder, Functional neuroimaging Core tip: We systematically reviewed the functional magnetic resonance imaging studies on adults affected by internet addiction disorder IADwithout any other psychiatric condition.

We found 18 studies, mostly conducted in East Asia and enrolling young males with internet gaming disorder.

IAD is not classified as a mental disorder in the Diagnostic and Statistical Manual of Mental Disorders-fifth edition, but a subtype of IAD, the internet gaming disorder IGD also called videogame addictionis included in the section 3 as a topic deserving future studies[ 2 ].

A higher prevalence of IAD was significantly associated with lower subjective and environmental conditions. Due to their high computer skill and easy Internet access, young adults are at augmented risk for IAD[ 5 ].

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Functional imaging techniques increase the possibility to investigate the neural basis of IAD, enhancing the sensitivity and the statistical power of clinical data.

Functional magnetic resonance imaging fMRIin particular, is a worldwide used non-invasive technique to study the neural underpinnings of psychiatric disorders[ 10 - 12 ]. Metabolic activity changes in the brain can be monitored during the execution of paradigms task related fMRI or during the spontaneous cerebral activity resting state fMRI [ 13 - 16 ]. In turn, he was able to use more violence to increase revenue. An establishment that refused to purchase liquor from him often got blown up, and as many as people were killed in such bombings during the s.

Rivals saw Capone as responsible for the proliferation of brothels in the city.

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He was particularly known for his flamboyant and costly jewelry. His favorite responses to questions about his activities were: On September 20,the North Side Gang used a ploy outside the Capone headquarters at the Hawthorne Inn, aimed at drawing him to the windows. Gunmen in several cars then opened fire with Thompson submachine guns and shotguns at the windows of the first-floor restaurant.

Capone was unhurt and called for a truce, but the negotiations fell through.

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The owner of Hawthorne's restaurant was a friend of Capone's, and he was kidnapped and killed by Moran and Drucci in January Capone is generally seen as having an appreciable effect in bringing about the victories of Republican William Hale Thompsonespecially in the mayoral race when Thompson campaigned for a wide open town, at one time hinting that he'd reopen illegal saloons.

In the mayoral race, Thompson beat William Emmett Dever by a relatively slim margin. Voting booths were targeted by Capone's bomber James Belcastro in the wards where Thompson's opponents were thought to have support, on the polling day of April 10,in the so-called Pineapple Primarycausing the deaths of at least 15 people. Belcastro was accused of the murder of lawyer Octavius Granady, an African American who challenged Thompson's candidate for the African American vote, and was chased through the streets on polling day by cars of gunmen before being shot dead.

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Four policemen were among those charged along with Belcastro, but all charges were dropped after key witnesses recanted their statements. An indication of the attitude of local law enforcement to Capone's organization came in when Belcastro was wounded in a shooting; police suggested to skeptical journalists that Belcastro was an independent operator.

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Cermak winning the mayoral election on April 6, Capone bought the estate in and lived there until his death in It is believed that Capone plotted the infamous February 14, St. Valentine's Day Massacre while living in the mansion.

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Moran was the last survivor of the North Side gunmen; his succession had come about because his similarly aggressive predecessors Vincent Drucci and Hymie Weiss had been killed in the violence that followed the murder of original leader Dean O'Banion.

On the morning of Thursday, February 14,[52] [53] Capone's lookouts signaled gunmen disguised as police officers to initiate a "police raid". The faux police lined the seven victims along a wall and signaled for accomplices armed with machine guns and shotguns. Photos of the slain victims shocked the public and damaged Capone's reputation.

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Within days, Capone received a summons to testify before a Chicago grand jury on charges of federal Prohibition violations, but he claimed to be too unwell to attend. One story, however, has Capone, having discovered that three of his men—Scalise, Anselmi, and Giunta—were conspiring against him with a rival gangster, Joe Aiello, reportedly arranging for the conspirators to dine with him and his bodyguards. The red trail of Chicago gangland from prohibition to Jake Lingle.

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He was charged with contempt of court for feigning illness to avoid an earlier appearance. A week after his release in MarchCapone was listed as the number one "Public Enemy" on the unofficial Chicago Crime Commission 's widely publicized list.

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Capone claimed that Miami police had refused him food and water and threatened to arrest his family. He was charged with perjury for making these statements, but was acquitted after a three-day trial in July. In court, Judge James Herbert Wilkerson intervened to reinforce questioning of Capone's doctor by the prosecutor. Wilkerson sentenced Capone to six months, but he remained free while on appeal of the contempt conviction. She tested this approach by prosecuting a South Carolina bootlegger.

Wilson to investigate Capone, with the focus on his spending. The key to Capone's conviction on tax charges was proving his income, and the most valuable evidence in that regard originated in his offer to pay tax. Ralph, his brother and a gangster in his own right, was tried for tax evasion in Ralph spent the next three years in prison after being convicted in a two-week trial over which Wilkerson presided.

Hence, without any investigation, the government had been given a letter from a lawyer acting for Capone conceding his large taxable income for certain years. InCapone was charged with income tax evasionas well as with various violations of the Volstead Act Prohibition at the Chicago Federal Building in the courtroom of Judge James Herbert Wilkerson.

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